Migraines are throbbing headaches that are normally very intense, occurring in just one half of the head. They can affect people of all ages and their cause is unknown. What is known is that during a migraine attack, blood vessels located in the brain dilate. This dilation causes the blood vessels to draw in on each other which stimulate the nerve endings near to these blood vessels. It is this that is thought to cause the pain.

Migraine

Migraines are fairly common occurrences, affecting nearly 20% of women and 6% of men during their lifetimes. Triggers for the migraine attack can vary, but some people are very aware that eating certain foods such as chocolates, cheese or citrus fruits can bring on an attack. Some other things that have been known to trigger migraines include anxiety, stress, exercise, loud noise, bright lights, traveling and the contraceptive pill. Many women appear to have attacks on or around the time of the menstrual periods.

When people describe migraines, they are commonly associated with headaches of varying degrees. These can include headaches occurring in bouts of approximately four to 72 hours; headaches on one side of the head; headaches throb and get worse with physical activity; nausea accompanied by vomiting; and other symptoms associated with sensitivity to light.

Migraines are treated by using painkillers. Which type depends on the severity and length of bouts being suffered.

Tuberculosis is a condition which primarily affects the lungs.  The bacteria which cause tuberculosis are slow moving bacteria and a person who has been infected might not have any symptoms for months or years afterwards.  The infection can spread to other parts of the body such as the nervous system or the bones.  Symptoms of tuberculosis include a cough that won’t go away, night sweats and weight loss but most of the time the immune system will kill off the bacteria and there will be no symptoms.  Sometimes, if the immune system cannot kill the bacteria it will build up a defense to the infection and it will stay in the body but no symptoms will be experienced, however, sometimes the body just cannot fight the bacteria and the infection spreads to the lungs and becomes known as active tuberculosis.  It can happen that in cases where the infection has lain dormant in the body in can become active at a later date.

Tuberculosis

Tuberculosis was a major disease many years ago and resulted in many deaths, but the introduction of antibiotics and vaccinations helped to reduce this.  In recent years though, tuberculosis cases have been increasing again, especially in ethnic minorities who have come from areas where tuberculosis is still widespread. Areas where the disease is widespread include countries of Africa south of the Sahara desert, Eastern Europe, Central America, South East Asia, and Russia.

If tuberculosis is not treated it can be deadly as it can result in the person not being able to breath properly. Treatment with antibiotics for tuberculosis usually involves taking a course for at least six months.

Down syndrome is a genetic disorder otherwise known as trisomy and it is where an individual has inherited an additional or extra copy of a particular chromosome. In the case of Down’s syndrome, the affected individuals have three copies rather than two of chromosome 21. The consequence of this additional copy is that it changes the balance of the body resulting in characteristic intellectual and physical features.

Down Syndrome

There are three kinds of Down’s syndrome: regular trisomy 21 which is where all the cells in the body have an extra chromosome 21 and is the most common type of the condition with nearly 94% affected with Down’s having it; translocation, which is where extra chromosome 21 material attaches to another chromosome, and four percent have this type; and mosaic, which is where only some of the cells have additional chromosome 21. This usually has milder features than the other two types and only two percent of affected individuals have mosaic.

Down syndrome sufferers look different to normal people and usually have a flat type of facial profile with eyes slanting upwards. Smaller ears, protruding tongue and a flat back of the head are other features. Individuals affected tend to be shorter than normal, have poor muscle tone and have broad, short hands. Half the affected individuals have a heart defect, which can be treated in some, but not others. Some have problems with their gut, making it difficult to eat while increasing the risk of constipation and thyroid problems.

There is no cure for Down syndrome but there are treatments available for the accompanying symptoms as well as support for the learning difficulties.